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KMID : 0606920080160020069
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Biomolecules & Therapeutics
2008 Volume.16 No. 2 p.69 ~ p.76
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Immunomodulatory Actions of Lysophosphatidylcholine
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Hong Chang-Won
Song Dong-Keun
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Abstract
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Lysophosphatidylcholine (LPC) is an endogenous phospholipid. LPC has various stimulating or modulating activities on immune cells, including lymphocytes, monocytes/macrophages and neutrophils. Studies generally revealed pro-inflammatory activities of LPC, but accumulating evidence indicates that LPC has also anti-inflammatory actions. Here we summarize immunomodulatory actions of LPC.
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KEYWORD
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Lysophosphatidylcholine, Lymphocyte, Monocyte, Macrophage, Neutrophil
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